Best Houston vs Duke Player Props: Flagg, Cryer To Dominate In Final Four Matchup

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Let’s break down our best Duke vs Houston player props for Saturday’s Final Four matchup.

Duke has looked like the best team in the field over the duration of the tournament so far, but they have not faced a defense like Houston quite yet. Both of these teams had decisive wins in their Elite 8 matchups, too.

Houston defeated the Tennessee Volunteers 69-50, while Duke took care of business against Alabama and won 85-65. Can the Houston defense do enough to slow down this Duke team, and keep them in the game, or will the Duke offense overpower the Cougars and cruise into the championship game? Who will likely become favorites on the March Madness odds board? Let’s dive in to our best Duke vs Houston player props and find out.

And don’t forget: Before making any Final Four wagers, be sure to grab the most favorable college basketball odds from North America’s best sportsbooks.

This game has a very low expected total of 135.5, so points should come at a premium on Saturday night. Cooper Flagg is going to be the exception, as Duke is going to need him to create some magic on the offensive side.

Best Duke vs Houston player props

  • Duke Cooper Flagg | Over 18.5 points | -110 at FanDuel
  • Duke Cooper Flagg | Over 7.5 rebounds | -145 at FanDuel
  • Duke Kon Knueppe | Under 14.5 points | -114 at FanDuel
  • Houston Cougars LJ Cryer | Over 15.5 points | -110 at FanDuel
  • Houston Cougars Milos Uzan | Under 12.5 points | -125 at FanDuel

Looking for more Final Four predictions? Take a look at our Duke vs Houston picks and Florida vs Auburn picks.

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Duke Cooper Flagg | Over 18.5 points | -110 at FanDuel

We will start with my favorite Duke vs Houston player prop, which is going to be Cooper Flagg over 18.5 points.

This game has a very low expected total of 135.5, so points should come at a premium on Saturday night. Cooper Flagg is going to be the exception, as Duke is going to need him to create some magic on the offensive side, which we all know he is very capable of doing. Flagg averaged 19 points per game this season, so we only need him to hit his season average to cash this play.

In his last game, he did not hit this total against Alabama as the game ended in a blowout, and he was not needed or in the game for the final five minutes. This game I expect to be close from wire to wire, which will force Flagg to play the majority of the game. If this is the case, he will have no issue being able to cash his points prop of 18.5.

Duke Cooper Flagg | Over 7.5 rebounds | -145 at FanDuel

This time, we are taking his over on his rebounds at 7.5 as part of our best Duke vs Houston player props. I do anticipate Houston struggling to score in this game, which is reflected in the total being set at 135.5. This will only benefit a guy like Flagg, who can really use his big frame and secure missed shots from the Houston side. 

Like I said earlier, I do think this game stays close until the end, which will lead Flagg to playing a heavy dose of minutes in this contest. Cooper has also grabbed nine rebounds or more in two of his last three games.

Duke Kon Knueppe | Under 14.5 points | -114 at FanDuel

I alluded to this earlier, but I do see this being a low-scoring game, which the oddsmakers are expecting with the total being set at 135.5. The only player on the Duke side that I am comfortable taking over is Cooper Flagg, and that leaves guys like Kon Knueppel to go under.

Knueppel averaged just under 14.5 points per game this season, and I do not see him going over his season average. I am sure a ton of people are expecting Knueppel to go over in this game, as he scored 20+ points in each of his last two games. The issue is, Duke has not played any team who is even close to as talented on the defensive end as Houston. We also have seen Tyrese Proctor step up all tournament long and he will need his opportunities in this game as well, which should take away from Knueppel’s totals here. Let’s see Kon Knueppel go low as part of our best Duke vs Houston player props.

Houston Cougars LJ Cryer | Over 15.5 points | -110 at FanDuel

Cryer is the experienced veteran on this Houston team that has been here, and done this before. He has experience in the big moments as he has won the championship previously with Baylor. LJ Cryer averaged 15.5 points per game, and that is exactly what he needs to do in this game. I do think this team will rely on him more than normal, especially down the stretch.

For Houston to have any chance in this game, he is going to need to score at least 20 in my opinion. Look for Cryer to be aggressive early and often as he logs some serious minutes in this Final Four matchup.

Houston Cougars Milos Uzan | Under 12.5 points | -125 at FanDuel

Uzan is coming off a six-point performance against Tennessee, and he’s going to need to be a facilitator in this game against Duke. Uzan averaged 11.5 points per game this season, and he will need to score a full point and a half higher than his average to cash this prop. He also is the team’s leader in assists at 4.5 assists per game, and I do believe he will be facilitating LJ Cryer when he is on the court. Cryer needs to be the big scorer here, and Uzan needs to be the main facilitator for Houston to have a shot. He should go comfortably under this total. Let’s sweep our best Duke vs Houston player props.

Game information

Matchup Location Date & Time TV Coverage
Houston Cougars vs. Duke Blue Devils Alamodome, San Antonio, TX April 5, 2025, 8:49 PM ET CBS

Betting odds

Team Point Spread Moneyline Total (Over/Under)
Duke Blue Devils -5.5 -275 Over 136.5 (-110)
Houston Cougars +5.5 +225 Under 136.5 (-110)
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