NFL Week 18 Odds, Spreads and Moneylines: The Final Act of the Regular Season

© Kevin R. Wexler / USA TODAY NETWORK
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  • The NFL regular season climaxes with 16 divisional games
  • Will the NFC East see yet another new champion?
  • How many teams will still be in playoff contention at kickoff?

The final week of the season has arrived in the NFL. While several teams have the luxury of knowing their fate (good or bad), others are preparing for a final push to keep their season alive and to obtain a playoff berth.

NFL Week 18 odds will reflect the circumstances teams find themselves in, with several teams potentially resting their players to preserve them for the playoffs or the next year. However, there are still plenty of competitive matches across the league for bettors to tap into.

Here, we will provide our thoughts on NFL Week 18 odds, matchups, and much more. First, let’s take a look at the full odds board.

NFL Week 18 odds

Matchup Time (ET) Moneyline Spread Total
Panthers at Falcons tbc tbc tbc tbc
Commanders at Cowboys tbc tbc tbc tbc
Chiefs at Broncos tbc tbc tbc tbc
Vikings at Lions tbc tbc tbc tbc
Bears at Packers tbc tbc tbc tbc
Texans at Titans tbc tbc tbc tbc
Jaguars at Colts tbc tbc tbc tbc
Chargers at Raiders tbc tbc tbc tbc
Seahawks at Rams tbc tbc tbc tbc
Bills at Patriots tbc tbc tbc tbc
Dolphins at Jets tbc tbc tbc tbc
Giants at Eagles tbc tbc tbc tbc
49ers at Cardinals tbc tbc tbc tbc
Bengals at Steelers tbc tbc tbc tbc
Saints at Buccaneers tbc tbc tbc tbc
Browns at Ravens tbc tbc tbc tbc

NFL Week 18 opening odds

NFL Week 18 odds will be released following the conclusion of Sunday NFL Week 17 games. All NFL Week 18 betting lines will be updated here as soon as they are available.

NFL Week 18 betting lines

*Note: all previews are made under the assumption every team is playing its best roster.*

Panthers at Falcons

The offseason departures of Brian Burns and Frankie Luvu mean that the Panthers’ slim chances of competing are even slimmer, especially against a Falcons squad that is the odds-on favorite to win the NFC South.

Commanders at Cowboys

Sam Howell led a surprising 26-6 victory over the Cowboys in Week 18 two years ago. Although that was not that long ago, this is an entirely different team, and one that is looking to reverse the franchise’s historical fortune against their rivals. Washington head coach Dan Quinn and DC Joe Whitt Jr. were both with the Cowboys last year and could have insider knowledge on the best ways to slow them down.

Chiefs at Broncos

The Chiefs are used to resting their guys in the final week of the season, but regardless of who is on the field, they’re more than capable of beating the Broncos. The Sean Payton hire looks worse and worse as the roster is still below league average and the results haven’t vindicated his hiring.

Vikings at Lions

Two NFC North rivals will meet in a matchup that could be crucial for playoff seeding. The Vikings are expected to finish last in the division but still have plenty of impact players and a defense that improved in 2023, while Detroit is the team with a target on its back.

Bears at Packers

What’s that? Another NFC North matchup? Caleb Williams will make his first trip to the frozen tundra as he looks to exact revenge on the Packers after years of torment by Aaron Rodgers, who told Bears fans he “still owned” them in Chicago in his final year with the team.

Texans at Titans

Houston was red-hot to finish the regular season last year and won a playoff game but got annihilated in the division round. They’ll use the opportunity to play the Titans to try to build momentum as they prepare for another run in the postseason.

Jaguars at Colts

The Colts barely missed out on a playoff spot when they fell in Week 18 last year. The Jaguars are still a competitive team, albeit one with a worse roster than they had in 2023, and this should be a game played within very fine margins.

Chargers at Raiders

Justin Herbert is widely regarded as one of the top seven or eight quarterbacks in the NFL, yet he doesn’t have a single playoff win on his resume. The expectation is that he’ll at least be in a position to end that this year, but he’ll need to get past a tough, hard-nosed Raiders team first.

Seahawks at Rams

Both teams have established quarterbacks, talented receivers, and solid defensive pieces, yet both are often overlooked because of the 49ers and have many players with points to prove. This should be one of the closest games of the final week with both potentially looking to sneak into the postseason.

Bills at Patriots

The Patriots took their pound of flesh off of the Bills last year but will be hard-pressed to replicate that. Even with Buffalo experiencing some internal turmoil, they’re much further ahead than New England in roster construction, chemistry, and overall performance.

Dolphins at Jets

A good old offense-versus-defense showdown, the Dolphins’ speedy playmakers will go up against the imposing defense of the Jets under the bitter cold of the New York winter. The eventual winner of this game could be the team that steps up on its “weaker” side of the football (though both units are still solid at worst).

Giants at Eagles

The Saquon Barkley revenge game will be out in full force as the Eagles host the Giants in the final week of the season. NFL Week 18 odds and futures odds portray the Eagles as clear-cut favorites, which is easy to understand given the Giants’ poor production at quarterback and lack of playmakers.

49ers at Cardinals

The Niners have the best roster in the NFL from top to bottom and the Cardinals, well, they don’t. San Fran’s style of play allows them to beat lesser teams even with backups in the game, which could very well play out here.

Bengals at Steelers

The Bengals-Steelers matchup should be one of the best of the week. Mike Tomlin has never had a losing record as a head coach and will lead his troops into a familiar end-of-season showdown against a divisional opponent looking to work its way into the playoffs.

Saints at Buccaneers

Both teams have question marks at several positions, but the Buccaneers are the more proven of the two. Not only did they win the division last year, but they got younger at many positions, while the Saints are insistent on sticking with aging players without putting much stock into the future.

Browns at Ravens

Buckle up, America. This is a trainwreck in the best way possible, as two of the league’s most physical teams are prepared to square off on Monday Night Football. Both teams want to run the ball and assert their will, setting up a great final cameo of the NFL regular season.

NFL Week 18 picks and predictions

Dan Campbell takes risks, and that includes playing his starters when he doesn’t need to. The Lions are better than the Vikings and could run up the score and cover the NFL Week 18 spread if Campbell sticks to his usual M.O.

The Texans roared into the postseason in 2023 and have even greater expectations this time around. The Titans got better all over their roster but still have tons of holes and were awful against the pass last year, which is a glaring concern against C.J. Stroud and company.

The Rams surprised many with their late-season turnaround and could be in position to finish their season on another positive note. The experience and steadiness of Matthew Stafford make them our pick on NFL Week 18 betting lines.

The Dolphins only beat one team with a winning record last year and can’t play in the cold. Regardless of however many concerns there are about an older Aaron Rodgers coming off an Achilles injury, the Jets on the NFL Week 18 spread is intriguing.

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